Class I B Agents Block INACTIVATED Na channels Slow phase 0 depolarisation- Slows upstroke of AP Shorten APD and ERP Ratio ERP/APD is increased Greate
{"Image DocumentName": "Class I B Agents Block INACTIVATED Na channels", "Image ImageDescription": "Slow phase 0 depolarisation- Slows upstroke of AP. Shorten APD and ERP. Ratio ERP/APD is increased. Greater affinity for ischaemic tissue that has more inactivated channels, little effect on normal cells \u2013 dissociates quickly (0.5sec) Lignocaine: VT in heart with normal EF. Phenytoin.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}