In patients with stage I or II disease, the following factors are considered unfavourable and, if present, will increase the intensity of the recommended initial therapy:
{"Image DocumentName": "In patients with stage I or II disease, the following factors are considered unfavourable and, if present, will increase the intensity of the recommended initial therapy:", "Image ImageDescription": "Large mediastinal adenopathy. An ESR result (a general marker of inflammation) 50 mm/h or higher, if the patient is otherwise asymptomatic OR ESR > 30 if hv B symptoms. More than 3 sites of disease involvement. The presence of B symptoms. The presence of extranodal disease. Age above 50 at diagnosis.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}