Production of MCP-1 and IL-8 in C6 glioma. C6 cells were treated with ATP (100 μM) in the presence, or absence, of gadolinium (Gd3+, 1 μM) for 48 h. (A) Levels of MCP-1 production (ng/ml) and (B) levels of IL-8 production (pg/ml) for the different treatments. Data are presented as mean ± SEM from 4 independent experiments. * indicates significant difference from control (p < 0.001) and ** indicates significant difference from ATP-treated group (p < 0.05).
{}