PDAC GEMM cross sectional studies a , Representative micrographs of H E stained pancreas from 16 days old control mice (left panel) and PKT mice presenting with (right panel, encircled) and without (middle panel) PanIN lesions. Scale bars: 100 μm. b , Ct values following qPCR analyses for oncogenic KRAS G12D , wild-type KRAS and 18S internal control RNA from exosomes of 44–48 days old PKT mice serum segregated using FACS for GPC1 + bead bound exos (red) and GPC1 − bead bound exos (blue). Data is presented as the mean ± standard deviation.
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