WHI: Effect of E+P on Stroke Incidence
{"Image DocumentName": "WHI: Effect of E+P on Stroke Incidence", "Image ImageDescription": "Women s Health Initiative. WHI: Effect of E+P on Stroke Incidence. Events (per 10,000 person-years) One of the hypotheses for the increase in all-cause dementia in the HT group reported in the WHIMS is that it reflects the increase in the risk of stroke or silent ischemic disease reported in the estrogen-plus-progestin arm of the WHI. This slide shows the number of cases of stroke per 10,000 person-years as a function of year of follow-up and as a function of whether the women were randomized to receive E+P or E alone. The E+P group had an increased incidence of stroke at Years 2, 3, and 4 that tended to reverse at Year 6. These data parallel those for dementia, which demonstrated an increase in probable all-cause dementia in Years 2, 3, and 4. Thus the incidence of dementia seems to follow that of stroke, supporting the idea that the E+P might have increased dementia by exacerbating ischemic stroke, even if silent. Year of Follow-up. Writing Group for the Women s Health Initiative Investigators. JAMA. 2002;288: Writing Group for the Women s Health Initiative Investigators. JAMA. 2002;288:", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}