Summary of Chromosome Anomalies
{"Image DocumentName": "Summary of Chromosome Anomalies", "Image ImageDescription": "Change in number. e.g. trisomy 21 Down syndrome; Edwards\u2019 syndrome; Turner syndrome. Usually an isolated occurrence. Change in structure. e.g. deletions. May be inherited. Down\u2019s Syndrome. An example of a chromosomal abnormality which causes learning difficulties. The karyotype shows a case of Down\u2019s syndrome (trisomy 21) For more information about Down\u2019s syndrome, visit:  [NOTES FOR TRAINING FACILITATORS IN CASE OF QUESTIONS ONLY. In total, there are normally 23 pairs of chromosomes, but in a trisomy there is an extra chromosome (tri somy = three bodies) A normal karyotype is written 46,XY or 46,XX. The karyotype, or complement of chromosomes, seen in a regular trisomy 21 is written as 47,XX +21 if female or 47, XY +21 if male. Note that Down\u2019s syndrome can be inherited, although this is rare. These cases are due to a change in chromosome structure (a translocation)] Trisomy 21.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}