Comprehensive diagnostic approach Morphology/cytochemistry As above Immunophenotyping (refined panel) First step : cyMPO, CD117, TdT, cyCD3, CD7, cyCD
{"Image DocumentName": "Comprehensive diagnostic approach", "Image ImageDescription": "Morphology/cytochemistry. As above. Immunophenotyping (refined panel) First step: cyMPO, CD117, TdT, cyCD3, CD7, cyCD79a, CD19, CD13, CD33, CD34, HLA-DR. Second step: - B-ALL: CD10, CD20, CD22, cyIgM, sIg, CD52, CD45, CD58, Ng2 or CD133, CD66c. - T-ALL: CD1a, CD2, CD3, CD5, CD4, CD8, CD52, CD99. Cytogenetics. As above; whenever possible, other approaches such as CGH and aCGH may be performed. Molecular genetics. Detection of fusion genes as required for risk stratification. Detection of Ig/TCR rearrangements. Gene expression profilling (research/diagnosis purposes) Recommendations of the EWALL Group, 2012.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}