Domain diagram and simple structural schematic of the newly postulated auxin responsive transcriptional regulatory complex(A) Domain diagrams of a typical Aux/IAA repressor family protein and a typical Auxin Response Factor (ARF) transcription factor. (B) A highly simplified structural schematic of an ARF regulatory complex in the absence of auxin. An ARF dimer is bound to an Auxin Response Element (AuxRE) inverted repeat. ARF and Aux/IAA PB1 domains form multimers, interacting via positive and negative faces. Structural data exist for domains with solid colors and lines, whereas dashed lines represent domains of unknown structure.DBD, DNA-binding domain, DD, dimerization domain; B3, B3 DNA-binding domain; AD, ancillary domain; MR, middle region; PB1, PB1 protein-protein interaction domain; EAR, EAR motif corepressor-binding domain; Deg, degron motif; N, N-terminus; C, C-terminus.
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