The novel drug-device combination developed by a team from Harvard's Wyss Institute and the New England Center for Stroke Research works quickly to re-vascularize a vessel obstructed by a blood clot. In this schematic, the re-vascularization process is depicted from left to right. An intra-arterial stent is used to open a small channel in the blood clot, restoring enough blood flow to trigger the clot-busting nanotherapeutic, which is activated by physical cues of fluid shear force.
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