The effect of p38 MAPK siRNA on the phosphorylation of p38 MAPK in PMA-induced MUC16 mRNA expression in the NCI-H292 airway epithelial cells. MUC16 mRNA expression was analyzed using reverse transcriptase-polymerase chain reaction (RT-PCR), real-time PCR. The knockdown of p38 MAPK by p38 MAPK siRNA significantly blocked PMA-induced MUC16 mRNA expression. MAPK, mitogen-activated protein kinase; PMA, phorbol 12-myristate 13-acetate; siRNA, small interfering RNA; GAPDH, glyceraldehyde-3-phosphate dehydrogenase. * P
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