Mechanisms of Action of Antibody Immunotherapy in CancerMechanisms of anticancer antibody therapies are diverse and represent the versatility of antibody-based approaches. Here, four different strategies are depicted. Upper left: direct cytotoxicity, in which mAbs can induce direct cytotoxicity in tumor cells by perturbing oncogenic signaling pathways or in which immunoconjugates can carry cytotoxic agents to targeted cells.
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