Comparison of ribbon representations of the hTra2-β RRM in complex with [5′-(GAAGAA)-3′] RNA (A); and the first RRM domain of poly pyrimidine-tract binding protein (PTBP RRM1) (PDBID: 2AD9) (B). In both structures, the N-terminal extension is colored cyan (the side-chain of the Pro residue in the N-terminal extension is depicted in blue), and the C-terminal extension is colored magenta (the side chain of Pro199 of the hTra2-β RRM, and the Leu residue of the PTBP RRM1 in the C-terminal extension are depicted in red). The side chain of the aromatic ring residue located at the end of the β4 strand and the side chains interacting with the residue in the C-terminal extension on the β-sheet surface are depicted in green. The RNA molecule is shown in gold.
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