Biochemistry and synthesis of thyroid hormones Formed as a complex between tyrosine and iodine –Iodine Limited factor in terrestrial mammals –Stored in follicular cells against electrical gradient –Use of Na/I co-transporter and Na/K-ATPase pump Oxidized by peroxidase –Incorporation in tyrosyl group of thyroglobulin (TG) –Formation of monoiodotyrosine and diiodotyrosine
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