Regulation of CRMP4 promoter activity by CpG modification (a) Illustration of the four CRMP4 promoter-driven luciferase reporters designated as A+ (−867/+114), A− (−839/+114), B+ (−717/+114), and B− (−656/+114). (b) Luciferase activities of the four CRMP4 promoter reporters that were pre-treated with or without M.SssI. One-way ANOVA was used to analyze the difference among the four groups luciferase reporters designated, and the differences between groups determined by the Student's t -test were considered to be significant at a P value less than 0.05/3 after correction. The error bars in b are s.e.m.
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