Platelet transfusion attenuates ECC-induced pulmonary inflammation. Mice were subjected to ECC for 30 min, treated as described in the legend to Fig. 2 , and then the right lung was harvested 1 h later, homogenized, and centrifuged. Samples were assayed for TNF-α ( A ), neutrophil elastase ( B ), and TGF-β ( C ) using commercial ELISA kits. Levels of TGF-β correlated negatively with TNF-α ( D ) and with neutrophil elastase ( E ). Data shown are mean ± SEM.
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