Cryopreservation Mechanisms of structural alteration
{"Image DocumentName": "Cryopreservation Mechanisms of structural alteration", "Image ImageDescription": "Related to an activation of metalloproteinases (MMPs) upon thawing, and disruption of normal extracellular matrix metabolism by the valve interstitial cells, a function shown to be impaired in cryopreserved tissue. Side specific cell phenotypes and differences in extracellular matrix organization may account for the heterogeneity in extracellular matrix alteration. The lack of crimp in the thawed cryopreserved valves suggests that the biomechanical properties of the ventricularis layer have been altered.", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}