Absence of β-catenin does not affect spontaneous or glucocorticoid-induced death of thymocytes. (a) Percentage of surviving thymocytes gated on CD45.1+ (WT donor) or CD45.2+ (β-catenin−/− donor) derived from mixed BM chimeras after 12 h of culture at 37°C. The percentage of surviving cells is normalized to control cells maintained at 4°C. Data represent mean ± SD of five experiments. (b) Glucocorticoid-induced cell death in WT (CD45.1+) and β-catenin−/− (CD45.2+) CD4+ CD8+ DP thymocytes after 12 h of culture at 37°C. Data are normalized to untreated controls and represent mean ± SD from five individual experiments.
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