Histone chaperones Eukaryotic Replication needs to deal with the
{"Image DocumentName": "Histone chaperones Eukaryotic Replication needs to deal with the", "Image ImageDescription": "nucleosome packaging of eukaryotic DNA. \u2022 Needs to Remove Histones upstream from the replication fork such that. replication is not impeded. \u2022 Needs to reassemble histones/nucleosomes on newly replicated DNA to. maintain chromatin structure and epigenetic marks. Histone chaperones. Example of Asf1, an H3/H4 histone chaperone that interacts with MCM. MCM. Replication. Asf1 remove H3/H4 histones. upstream from MCM and reloads. them after replication has proceeded. H3/H4. Asf1 can also add new H3/H4 histones since there is only \u00bd of the histones needed on the parental DNA. Science 21 December 2007: Vol no. 5858, pp", "Image XResolution": "37", "Image YResolution": "37", "Image ResolutionUnit": "Pixels/Centimeter", "Image Software": "SlidePlayer", "Image YCbCrPositioning": "Centered"}