EV71-specific antibody responses measured in serum from BALB/c mice immunised with CpG as an adjuvant for a formalin-inactivated EV71 vaccine. Mice were intranasally immunised with PBS, formalin-inactivated EV71 (5 μg/dose), or formalin-inactivated EV71 (5 μg/dose) plus CpG (20 μg/dose) three times at 3-week intervals. ELISA was used to measure EV71-specific IgG ( a ) and EV71-specific IgA ( b ) in the serum of mice at 2 weeks after the third immunisation. Values shown are means ± SEMs of six mice in each experimental group; * p
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